Health Book Citation

In intrinsic acute kidney injury there is structural kidney damage that can be the consequence of primary kidney disease a complication of another disease in a distant organ drug toxicity or prolonged hypo perfusion. Its causes are numerous.

Acute Kidney Injury A Guide To Diagnosis And Management American Family Physician

Diseases that cause intrinsic injury to the kidney proper glomeruli tubules interstitium small blood vessels are grouped under renal causes or intrinsic causes e g acute glomerulonephritis acute tubular necrosis acute interstitial nephritis or small vessel vasculitis.

Intrinsic acute kidney injury. Intrinsic renal causes are also important sources of acute kidney injury and can be categorized by the component of the kidney that is primarily affected i e tubular glomerular interstitial. The approach to intrinsic renal injury varies according to the affected part of the kidney. Aki is diagnosed on the basis of characteristic laboratory findings such as ele.

The term tubular necrosis is a misnomer as true cellular necrosis is usually minimal and the alteration is not limited to the tubular structures. Generally it occurs because of damage to the kidney tissue caused by decreased kidney blood flow from any cause exposure to substances harmful to the kidney an inflammatory process in the kidney or an obstruction of the urinary tract that impedes the flow of urine. Most commonly caused by sepsis infection ischemia and or nephrotoxins.

Once hemodynamic and postrenal causes of aki have been excluded acute renal dysfunction that is intrinsic to the kidneys must be considered. Acute kidney failure is most common in people who are already hospitalized particularly in critically ill people who need intensive care. Acute kidney failure can be fatal and requires intensive treatment.

Intrinsic acute kidney injury 35 of cases intrinsic causes include any disease that leads to severe direct kidney damage. Intrinsic causes of acute kidney injury anitha vijayan introduction the overall management of a patient with acute kidney injury aki as well as pre and postrenal aki was covered in chapter 7. Glomerulonephritis e g rapidly progressive glomerulonephritis vascular.

The most common cause of acute kidney injury aki is acute tubular necrosis atn when the pattern of injury lies within the kidney intrinsic disease. Acute kidney failure also called acute renal failure or acute kidney injury develops rapidly usually in less than a few days. Acute kidney injury aki in the intensive care unit icu can be the result of a wide range of disease processes so that it is likely to be encountered by physicians from all specialties.

The increasing recognition of the overlap between critical care medicine and nephrology has resulted in what nowadays is called critical care nephrology. Acute tubular necrosis causes 85 of intrinsic akis. Intrinsic renal causes of acute kidney injury are categorized by the location of the injury most commonly the glomerulus or tubule and include the interstitial or vascular portions of the kidney.

Acute kidney injury previously called acute renal failure is an abrupt loss of kidney function that develops within 7 days.

Popular Posts

Featured Post

Pharmacology Math For Nurses

34 pharmacology math learning objectives 1. A nurse s ultimate guide to accurate drug dosage calculations. Nursing Maths Medication Math ...